CHE 3300 - MEDICINAL CHEMISTRY

credits: 3.0
Crosslisted/Same As: BIO 3300
BIO 3300-CHE 3300, will focus on the synthesis and design of pharmaceuticals. Students will review various drug classes pertaining to neurotransmission, the central nervous, cardiovascular and immune systems. The biological and chemical mode of actions and the development of new drugs will be examined. Organic design and the biochemical implications of structure will be evaluated along with QSAR (Qualitative Structure Activity Relationships). Objectives: A) Identify and compare the mode of actions of various drugs related to neurotransmission, the central nervous, cardiovascular and immune systems; B) Identify various drugs by class according to their structure; C) Explain the biochemical pathways of disease; F) Explain and summarize the rational design of the drugs studied. Method of Instruction: The course will be primarily lecture based and will involve chalkboard notes and projection of relevant images. The course will also involve class participation and discussion activities. The students will discuss various diseases and the approaches for treatment and cures. Method of Evaluation: The primary method of evaluation will be four test given throughout the semester, a final exam as well as paper and in class presentation.

Prerequisite(s): BIO 1020 - GENERAL BIOLOGY I and CHE 2010 - ORGANIC CHEMISTRY I